Bone microenvironment regulative hydrogels with ROS scavenging and prolonged oxygen-generating for enhancing bone repair

Large bone defects resulting from fractures and disease are a major clinical challenge, being often unable to heal spontaneously by the body's repair mechanisms. Lines of evidence have shown that hypoxia-induced overproduction of ROS in bone defect region has a major impact on delaying bone reg...

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Bibliographic Details
Main Authors: Han Sun, Juan Xu, Yangyufan Wang, Siyu Shen, Xingquan Xu, Lei Zhang, Qing Jiang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-06-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X22005096