Transcription factor p53 exhibits increased binding to the α2-macroglobulin gene promoter and decreased glycosylation in fetal and adult rat liver during the acute-phase response

The binding affinity of p53 for the MG promoter was assessed by DNA-affinity chromatography with the extended α2-macroglobulin (MG) gene promoter (-852/+12) and immunoblot analysis. During the increased MG gene transcription observed in the fetus and the acute-phase (AP) response in both the fetus a...

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Bibliographic Details
Main Authors: Mihailović Mirjana, Poznanović G., Dinić Svetlana, Grdović Nevena, Vidaković Melita, Martinović Vesna, Bogojević Desanka
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2008-01-01
Series:Archives of Biological Sciences
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2008/0354-46640803347M.pdf