Identification of hub genes and candidate herbal treatment in obesity through integrated bioinformatic analysis and reverse network pharmacology

Abstract Obesity is a global epidemic elevating the risk of various metabolic disorders. As there is a lack of effective drugs to treat obesity, we combined bioinformatics and reverse network pharmacology in this study to identify effective herbs to treat obesity. We identified 1011 differentially e...

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Bibliographic Details
Main Authors: Yuxing Tai, Hongying Tian, Xiaoqian Yang, Shixing Feng, Shaotao Chen, Chongwen Zhong, Tianjiao Gao, Xiaochao Gang, Mingjun Liu
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-22112-4