Two-Sample Mendelian Randomization Analysis Investigates Causal Associations Between Gut Microbial Genera and Inflammatory Bowel Disease, and Specificity Causal Associations in Ulcerative Colitis or Crohn’s Disease

Two-Sample Mendelian Randomization Analysis Investigates Causal Associations Between Gut Microbial Genera and Inflammatory Bowel Disease, and Specificity Causal Associations in Ulcerative Colitis or Crohn’s Disease

BackgroundIntestinal dysbiosis is associated with inflammatory bowel disease (IBD). Ulcerative colitis (UC) and Crohn’s disease (CD), two subtypes of IBD, are characterized by unique microbial signatures, respectively. However, it is unclear whether UC or CD has a specific causal relationship with g...

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Bibliographic Details
Main Authors: Bin Liu, Ding Ye, Hong Yang, Jie Song, Xiaohui Sun, Yingying Mao, Zhixing He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
inflammatory bowel disease
gut microbial genera
Mendelian randomization
ulcerative colitis
Crohn’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.921546/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.921546/full

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