Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex.

The galectin 3 binding protein (LGALS3BP, also known as 90K) is a ubiquitous multifunctional secreted glycoprotein originally identified in cancer progression. It remains unclear how 90K functions in innate immunity during viral infections. In this study, we found that viral infections resulted in e...

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Bibliographic Details
Main Authors: Gang Xu, Zhangchuan Xia, Feiyan Deng, Lin Liu, Qiming Wang, Yi Yu, Fubing Wang, Chengliang Zhu, Weiyong Liu, Zhikui Cheng, Ying Zhu, Li Zhou, Yi Zhang, Mengji Lu, Shi Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008002