Origin, activation, and targeted therapy of glioma-associated macrophages

Origin, activation, and targeted therapy of glioma-associated macrophages

The glioma tumor microenvironment plays a crucial role in the development, occurrence, and treatment of gliomas. Glioma-associated macrophages (GAMs) are the most widely infiltrated immune cells in the tumor microenvironment (TME) and one of the major cell populations that exert immune functions. GA...

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Bibliographic Details
Main Authors: Can Xu, Menglin Xiao, Xiang Li, Lei Xin, Jia Song, Qi Zhan, Changsheng Wang, Qisong Zhang, Xiaoye Yuan, Yanli Tan, Chuan Fang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Glioma
glioma associated macrophages (GAMs)
recruitment
polarization
therapy resistance
targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.974996/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.974996/full

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