Novel Self-Forming Nanosized DDS Particles for BNCT: Utilizing A Hydrophobic Boron Cluster and Its Molecular Glue Effect

Novel Self-Forming Nanosized DDS Particles for BNCT: Utilizing A Hydrophobic Boron Cluster and Its Molecular Glue Effect

BNCT is a non-invasive cancer therapy that allows for cancer cell death without harming adjacent cells. However, the application is limited, owing to the challenges of working with clinically approved boron (B) compounds and drug delivery systems (DDS). To address the issues, we developed self-formi...

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Bibliographic Details
Main Authors: Abdul Basith Fithroni, Kazuko Kobayashi, Hirotaka Uji, Manabu Ishimoto, Masaru Akehi, Takashi Ohtsuki, Eiji Matsuura
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Cells
Subjects:
boron neutron capture therapy (BNCT)
biologically self-degradable amphipathic polymer (Lactosome)
hydrophobic boron cluster
carborane isomers or <i>o</i>-carborane alkylated derivatives
molecular glue effect
Online Access:https://www.mdpi.com/2073-4409/11/20/3307

Internet

https://www.mdpi.com/2073-4409/11/20/3307

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