Extending the Structural Diversity of Labdane Diterpenoids from Marine-Derived Fungus <i>Talaromyces</i> sp. HDN151403 Using Heterologous Expression

Extending the Structural Diversity of Labdane Diterpenoids from Marine-Derived Fungus <i>Talaromyces</i> sp. HDN151403 Using Heterologous Expression

Heterologous biosynthesis has become an effective means to activate fungal silent biosynthetic gene clusters (BGCs) and efficiently utilize fungal genetic resources. Herein, thirteen labdane diterpene derivatives, including five undescribed ones named talarobicins A–E (<b>3</b>–<b>...

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Bibliographic Details
Main Authors: Falei Zhang, Chuanteng Ma, Qian Che, Tianjiao Zhu, Guojian Zhang, Dehai Li
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Marine Drugs
Subjects:
labdane diterpenoid
<i>Talaromyces</i> sp. HDN151403
heterologous expression
structural diversity
biosynthesis
Online Access:https://www.mdpi.com/1660-3397/21/12/628

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https://www.mdpi.com/1660-3397/21/12/628

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