Matrix-free human pluripotent stem cell manufacturing by seed train approach and intermediate cryopreservation
Abstract Background Human pluripotent stem cells (hPSCs) have an enormous therapeutic potential, but large quantities of cells will need to be supplied by reliable, economically viable production processes. The suspension culture (three-dimensional; 3D) of hPSCs in stirred tank bioreactors (STBRs) h...
Main Authors: | Kevin Ullmann, Felix Manstein, Wiebke Triebert, Nils Kriedemann, Annika Franke, Jana Teske, Mira Mertens, Victoria Lupanow, Gudrun Göhring, Alexandra Haase, Ulrich Martin, Robert Zweigerdt |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-03-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-024-03699-z |
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