Apo[a] size and PNR explain African American-Caucasian differences in allele-specific apo[a] levels for small but not large apo[a]

Apo[a] size and PNR explain African American-Caucasian differences in allele-specific apo[a] levels for small but not large apo[a]

Apolipoprotein [a] (apo[a]) gene size is a major predictor of lipoprotein [a] level. To determine genetic predictors of allele-specific apo[a] levels beyond gene size, we evaluated the upstream C/T and pentanucleotide repeat (PNR) polymorphisms. We determined apo[a] sizes, allele-specific apo[a] lev...

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Bibliographic Details
Main Authors: Jill Rubin, Han Jo Kim, Thomas A. Pearson, Steve Holleran, Rajasekhar Ramakrishnan, Lars Berglund
Format: Article
Language:English
Published: Elsevier 2006-05-01
Series:Journal of Lipid Research
Subjects:
lipoprotein [a]
African Americans
genotyping
polymorphism
apolipoprotein [a]
pentanucleotide repeat
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520332466

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http://www.sciencedirect.com/science/article/pii/S0022227520332466

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