A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates

Abstract We present a non-human primate mycobacterial growth inhibition assay (MGIA) using in vitro blood or cell co-culture with the aim of refining and expediting early tuberculosis vaccine testing. We have taken steps to optimise the assay using cryopreserved peripheral blood mononuclear cells, t...

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Bibliográfalaš dieđut
Váldodahkkit: Rachel Tanner, Andrew D. White, Charelle Boot, Claudia C. Sombroek, Matthew K. O’Shea, Daniel Wright, Emily Hoogkamer, Julia Bitencourt, Stephanie A. Harris, Charlotte Sarfas, Rachel Wittenberg, Iman Satti, Helen A. Fletcher, Frank A. W. Verreck, Sally A. Sharpe, Helen McShane
Materiálatiipa: Artihkal
Giella:English
Almmustuhtton: Nature Portfolio 2021-01-01
Ráidu:npj Vaccines
Liŋkkat:https://doi.org/10.1038/s41541-020-00263-7

Interneahtta

https://doi.org/10.1038/s41541-020-00263-7

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