A system-wide investigation of the dynamics of Wnt signaling reveals novel phases of transcriptional regulation.

Aberrant Wnt signaling has been implicated in a wide variety of cancers and many components of the Wnt signaling network have now been identified. Much less is known, however, about how these proteins are coordinately regulated. Here, a broad, quantitative, and dynamic study of Wnt3a-mediated stimul...

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Bibliographic Details
Main Authors: Taranjit S Gujral, Gavin MacBeath
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2850918?pdf=render