Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets

Generalized epilepsy affects 24 million people globally; at least 25% of cases remain medically refractory. The thalamus, with widespread connections throughout the brain, plays a critical role in generalized epilepsy. The intrinsic properties of thalamic neurons and the synaptic connections between...

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Bibliographic Details
Main Authors: Britta E. Lindquist, Clare Timbie, Yuliya Voskobiynyk, Jeanne T. Paz
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996123001080