Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets
Generalized epilepsy affects 24 million people globally; at least 25% of cases remain medically refractory. The thalamus, with widespread connections throughout the brain, plays a critical role in generalized epilepsy. The intrinsic properties of thalamic neurons and the synaptic connections between...
Main Authors: | Britta E. Lindquist, Clare Timbie, Yuliya Voskobiynyk, Jeanne T. Paz |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996123001080 |
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