Synthesis of α-amino amidines through molecular iodine-catalyzed three-component coupling of isocyanides, aldehydes and amines

Synthesis of α-amino amidines through molecular iodine-catalyzed three-component coupling of isocyanides, aldehydes and amines

A facile and efficient synthetic protocol for the synthesis of α-amino amidines has been developed using a molecular iodine-catalyzed three-component coupling reaction of isocyanides, amines, and aldehydes. The presented strategy offers the advantages of mild reaction conditions, low environmental i...

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Bibliographic Details
Main Authors: Praveen Reddy Adiyala, D. Chandrasekhar, Jeevak Sopanrao Kapure, Chada Narsimha Reddy, Ram Awatar Maurya
Format: Article
Language:English
Published: Beilstein-Institut 2014-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
α-amino amidines
iodine
isocyanide
multicomponent reaction
Ugi reaction
Online Access:https://doi.org/10.3762/bjoc.10.214

Internet

https://doi.org/10.3762/bjoc.10.214

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