Vascular dysfunction in a transgenic model of Alzheimer’s disease: Effects of CB1R and CB2R cannabinoid agonists.

Vascular dysfunction in a transgenic model of Alzheimer’s disease: Effects of CB1R and CB2R cannabinoid agonists.

There is evidence of altered vascular function, including cerebrovascular, in Alzheimer’s disease (AD) and transgenic models of the disease. Indeed vasoconstrictor responses are increased, while vasodilation is reduced in both conditions. β-Amyloid (Aβ) appears to be responsible, at least in part, o...

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Bibliographic Details
Main Authors: Jorge Navarro-Dorado, Nuria Villalba, Dolores Prieto, Begoña Brera, Ana María Martín-Moreno, Teresa Tejerina, Maria L. De Ceballos
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Neuroscience
Subjects:
beta-amyloid
Vascular Dysfunction
Alzheimer's disease (AD)
cannabioid receptors
Tg APP
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00422/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2016.00422/full

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