Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators

ABSTRACT Dysregulated and maladaptive immune responses are at the forefront of human diseases caused by infection with zoonotic viral hemorrhagic fever viruses. Elucidating mechanisms of how the natural animal reservoirs of these viruses coexist with these agents without overt disease, while permitt...

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Bibliographic Details
Main Authors: Joseph Prescott, Jonathan C. Guito, Jessica R. Spengler, Catherine E. Arnold, Amy J. Schuh, Brian R. Amman, Tara K. Sealy, Lisa W. Guerrero, Gustavo F. Palacios, Mariano Sanchez-Lockhart, Cesar G. Albariño, Jonathan S. Towner
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mSphere
Subjects:
Ebola virus
Marburg virus
immune response
rousette bat
viral hemorrhagic fever
virology
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00728-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00728-19

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