Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models

Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models

Alzheimer’s disease (AD) is the most common progressive neurodegenerative disease. The accumulation of amyloid-beta (Aβ) plaques is a distinctive pathological feature of AD patients. The aims of this study were to evaluate the therapeutic effect of chicoric acid (CA) on AD models and to explore its...

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Bibliographic Details
Main Authors: Ruonan Wang, Shijia Kang, Zirui Zhao, Lingling Jin, Xiaolin Cui, Lili Chen, Melitta Schachner, Sheng Li, Yanjie Guo, Jie Zhao
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
chicoric acid
amyloid-β plaques
L1CAM
Alzheimer’s disease
synaptic plasticity
Online Access:https://www.mdpi.com/1422-0067/25/6/3408

Internet

https://www.mdpi.com/1422-0067/25/6/3408

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