The critical role and potential target of the autotaxin/lysophosphatidate axis in pancreatic cancer

Autotaxin, an ecto-lysophospholipase D encoded by the human ENNP2 gene, is expressed in multiple tissues, and participates in numerous critical physiologic and pathologic processes including inflammation, pain, obesity, embryo development, and cancer via the generation of the bioactive lipid lysopho...

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Bibliographic Details
Main Authors: Ming Quan, Jiu-jie Cui, Xiao Feng, Qian Huang
Format: Article
Language:English
Published: IOS Press 2017-03-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317694544