The critical role and potential target of the autotaxin/lysophosphatidate axis in pancreatic cancer
Autotaxin, an ecto-lysophospholipase D encoded by the human ENNP2 gene, is expressed in multiple tissues, and participates in numerous critical physiologic and pathologic processes including inflammation, pain, obesity, embryo development, and cancer via the generation of the bioactive lipid lysopho...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-03-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317694544 |