A Bayesian Integrative Model for Genetical Genomics with Spatially Informed Variable Selection

We consider a Bayesian hierarchical model for the integration of gene expression levels with comparative genomic hybridization (CGH) array measurements collected on the same subjects. The approach defines a measurement error model that relates the gene expression levels to latent copy number states....

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Bibliographic Details
Main Authors: Alberto Cassese, Michele Guindani, Marina Vannucci
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S13784