T Lymphocyte Serotonin 5-HT<sub>7</sub> Receptor Is Dysregulated in Natalizumab-Treated Multiple Sclerosis Patients

T Lymphocyte Serotonin 5-HT<sub>7</sub> Receptor Is Dysregulated in Natalizumab-Treated Multiple Sclerosis Patients

Serotonin (5-HT) is known as a potent immune cell modulator in autoimmune diseases and should be protective in the pathogenesis of multiple sclerosis (MS). Nevertheless, there is limited knowledge about receptors involved in 5-HT effects as well as induced mechanisms. Among 5-HT receptors, the 5-HT&...

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Bibliographic Details
Main Authors: Flora Reverchon, Colleen Guillard, Lucile Mollet, Pascal Auzou, David Gosset, Fahima Madouri, Antoine Valéry, Arnaud Menuet, Canan Ozsancak, Maud Pallix-Guyot, Séverine Morisset-Lopez
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
serotonin
5-HT<sub>7</sub> receptor
multiple sclerosis
natalizumab treatment
T lymphocyte (T-cell)
PBMCs (peripheral blood mononuclear cells)
Online Access:https://www.mdpi.com/2227-9059/10/10/2418

Internet

https://www.mdpi.com/2227-9059/10/10/2418

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