Oxidative damage and mitochondrial dysfunction in cystathionine beta-synthase deficiency

Oxidative damage and mitochondrial dysfunction in cystathionine beta-synthase deficiency

Abstract Cystathionine beta-synthase deficiency (CBSD) is the most prevalent inherited disorder of homocysteine metabolism in the transsulphuration pathway. Research have suggested oxidative stress and inflammation as candidate pathogenic mechanisms in CBSD. This study aims to evaluate mitochondrial...

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Bibliographic Details
Main Authors: Mehmet Cihan Balci, Asuman Gedikbasi, Sukru Anil Dogan, Sevde Kahraman, Suzin Tatoryan, Sebnem Tekin Neijmann, Meryem Karaca, Fatmahan Atalar, Gulden Gokcay
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Cystathionine beta synthase deficiency
Fibroblast growth factor 21
Growth differentiation factor 15
Mitochondria
Oxidative stress
Online Access:https://doi.org/10.1038/s41598-024-80273-w

Internet

https://doi.org/10.1038/s41598-024-80273-w

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