Co-expression of distinct L1 retrotransposon coiled coils can lead to their entanglement

Abstract L1 (LINE1) non-LTR retrotransposons are ubiquitous genomic parasites and the dominant transposable element in humans having generated about 40% of their genomic DNA during their ~ 100 million years (Myr) of activity in primates. L1 replicates in germ line cells and early embryos, causing ge...

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Bibliographic Details
Main Authors: Nikola A. Mizgier, Charlie E. Jones, Anthony V. Furano
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Mobile DNA
Subjects:
Online Access:https://doi.org/10.1186/s13100-023-00303-8