The Effect of Alzheimer’s Disease-Associated Genetic Variants on Longevity

The Effect of Alzheimer’s Disease-Associated Genetic Variants on Longevity

Human longevity is influenced by the genetic risk of age-related diseases. As Alzheimer’s disease (AD) represents a common condition at old age, an interplay between genetic factors affecting AD and longevity is expected. We explored this interplay by studying the prevalence of AD-associated single-...

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Bibliographic Details
Main Authors: Niccolò Tesi, Marc Hulsman, Sven J. van der Lee, Iris E. Jansen, Najada Stringa, Natasja M. van Schoor, Philip Scheltens, Wiesje M. van der Flier, Martijn Huisman, Marcel J. T. Reinders, Henne Holstege
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Genetics
Subjects:
cognitively healthy
centenarians
aging
alzheimer’s disease
effect on aging
protective variants
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.748781/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.748781/full

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