The Immunogenicity and Properties of a Whole-Cell ETEC Vaccine Inactivated with Psoralen and UVA Light in Comparison to Formalin

Inactivated whole-cell vaccines present a full repertoire of antigens to the immune system. Formalin treatment, a standard method for microbial inactivation, can modify or destroy protein antigenic epitopes. We tested the hypothesis that photochemical inactivation with psoralen and UVA light (PUVA),...

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Bibliographic Details
Main Authors: Marlena M. Westcott, Maria Blevins, Thomas F. Wierzba, Alexis E. Morse, Kinnede R. White, Leigh Ann Sanders, John W. Sanders
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/11/8/2040