Inhibition of Ceramide Accumulation in Podocytes by Myriocin Prevents Diabetic Nephropathy

Inhibition of Ceramide Accumulation in Podocytes by Myriocin Prevents Diabetic Nephropathy

BackgroundCeramides are associated with metabolic complications including diabetic nephropathy in patients with diabetes. Recent studies have reported that podocytes play a pivotal role in the progression of diabetic nephropathy. Also, mitochondrial dysfunction is known to be an early event in podoc...

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Bibliographic Details
Main Authors: Chang-Yun Woo, Ji Yeon Baek, Ah-Ram Kim, Chung Hwan Hong, Ji Eun Yoon, Hyoun Sik Kim, Hyun Ju Yoo, Tae-Sik Park, Ranjan Kc, Ki-Up Lee, Eun Hee Koh
Format: Article
Language:English
Published: Korean Diabetes Association 2020-08-01
Series:Diabetes & Metabolism Journal
Subjects:
diabetic nephropathies
ceramides
mitochondria
podocytes
reactive oxygen species
thermozymocidin
Online Access:http://e-dmj.org/upload/pdf/dmj-44-581.pdf

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http://e-dmj.org/upload/pdf/dmj-44-581.pdf

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