RNA as a feasible marker of Trypanosoma cruzi viability during the parasite interaction with the triatomine vector Rhodnius prolixus (Hemiptera, Triatominae).

A recurring question concerning Trypanosoma cruzi DNA detection/quantification is related to the fact that DNA amplification, by itself, does not differentiate between viable or dead parasites. On the other hand, RNA can be considered a potential molecular marker of pathogens viability. Herein, we d...

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Bibliographic Details
Main Authors: Paula Finamore-Araujo, Gabriel Lucio Silva da Fonseca, Cecília Stahl Vieira, Daniele Pereira de Castro, Otacilio Cruz Moreira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010535