Upregulation of ERp57 promotes clear cell renal cell carcinoma progression by initiating a STAT3/ILF3 feedback loop

Abstract Background ERp57 dysfunction has been shown to contribute to tumorigenesis in multiple malignances. However, the role of ERp57 in clear cell renal carcinoma (ccRCC) remains unclear. Methods Cell proliferation ability was measured by MTT and colony forming assays. Western blotting and quanti...

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Bibliographic Details
Main Authors: Yan Liu, Jian-Xing Wang, Zi-Yuan Nie, Yue Wen, Xin-Ju Jia, Li-Na Zhang, Hui-Jun Duan, Yong-Hong Shi
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13046-019-1453-z