Integrated Solid-Phase Extraction, Ultra-High-Performance Liquid Chromatography–Quadrupole-Orbitrap High-Resolution Mass Spectrometry, and Multidimensional Data-Mining Techniques to Unravel the Metabolic Network of Dehydrocostus Lactone in Rats

Integrated Solid-Phase Extraction, Ultra-High-Performance Liquid Chromatography–Quadrupole-Orbitrap High-Resolution Mass Spectrometry, and Multidimensional Data-Mining Techniques to Unravel the Metabolic Network of Dehydrocostus Lactone in Rats

Dehydrocostus lactone (DL) is among the representative ingredients of traditional Chinese medicine (TCM), with excellent anticancer, antibacterial, and anti-inflammatory activities. In this study, an advanced strategy based on ultra-high-performance liquid chromatography–quadrupole-Orbitrap high-res...

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Bibliographic Details
Main Authors: Yingying Tian, Beibei Ma, Chuang Liu, Xinyue Zhao, Shangyue Yu, Yilin Li, Shiqiu Tian, Hailuan Pei, Zijian Wang, Zeping Zuo, Zhibin Wang
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Molecules
Subjects:
dehydrocostus lactone (DL)
UHPLC–Q-Orbitrap HRMS
solid-phase extraction (SPE)
data-mining techniques
metabolic network
Online Access:https://www.mdpi.com/1420-3049/27/22/7688

Internet

https://www.mdpi.com/1420-3049/27/22/7688

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