Avidin cooperative allosterism upon binding biotin observed by differential changes in intrinsic fluorescence

Similar to streptavidin, the binding of biotin by avidin does not appear to be cooperative in the traditional sense of altered binding strength, though it appears to be cooperative in terms of ligand induced structural communication across subunits in the protein as previously shown for streptavidin...

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Bibliographic Details
Main Authors: Mark J. Waner, Gianna Ellis, Meghan Graeca, Nicholas Ieraci, Cole Morell, Alycia Murphy, David P. Mascotti
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biochemistry and Biophysics Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580823001358