Cell-Culture–Dependent Change of Ca2+ Response of Rat Aortic Myocytes to Sphingosine-1-Phosphate

We characterized the effects of sphingosine-1-phosphate (S1P) on rat aortic myocytes with or without culture. Application of S1P induced a small Ca2+ response in 40% freshly dispersed aortic myocytes, whereas S1P caused a larger Ca2+ response in 90% myocytes cultured for 72 h. Concentration–response...

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Bibliographic Details
Main Authors: Ryoichi Tanaka, Katsuhiko Muraki, Susumu Ohya, Yuka Itoh, Noriyuki Hatano, Yuji Imaizumi
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319313969