Base-pairing of uracil and 2,6-diaminopurine: from cocrystals to photoreactivity

Base-pairing of uracil and 2,6-diaminopurine: from cocrystals to photoreactivity

Summary: We show that the non-canonical nucleobase 2,6-diaminopurine (D) spontaneously base pairs with uracil (U) in water and the solid state without the need to be attached to the ribose-phosphate backbone. Depending on the reaction conditions, D and U assemble in thermodynamically stable hydrated...

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Bibliographic Details
Main Authors: Tomislav Stolar, Ben K.D. Pearce, Martin Etter, Khai-Nghi Truong, Tea Ostojić, Andraž Krajnc, Gregor Mali, Barbara Rossi, Krešimir Molčanov, Ivor Lončarić, Ernest Meštrović, Krunoslav Užarević, Luca Grisanti
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:iScience
Subjects:
Chemistry
Theoretical photochemistry
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224011167

Internet

http://www.sciencedirect.com/science/article/pii/S2589004224011167

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