Association of LBX1 Gene Methylation Level with Disease Severity in Patients with Idiopathic Scoliosis: Study on Deep Paravertebral Muscles

Association of LBX1 Gene Methylation Level with Disease Severity in Patients with Idiopathic Scoliosis: Study on Deep Paravertebral Muscles

Idiopathic scoliosis (IS) is a multifactorial disease with a genetic background. The association of Ladybird Homeobox 1 (<i>LBX1</i>) polymorphisms with IS has been proven in multiple studies. However, the epigenetic mechanisms have not been evaluated. This study aimed to evaluate the &l...

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Bibliographic Details
Main Authors: Piotr Janusz, Małgorzata Tokłowicz, Mirosław Andrusiewicz, Małgorzata Kotwicka, Tomasz Kotwicki
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Genes
Subjects:
idiopathic scoliosis
scoliosis progression
DNA methylation
ladybird homeobox 1 gene (<i>LBX1</i>)
pyrosequencing
Online Access:https://www.mdpi.com/2073-4425/13/9/1556

Internet

https://www.mdpi.com/2073-4425/13/9/1556

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