BE4max and AncBE4max Are Efficient in Germline Conversion of C:G to T:A Base Pairs in Zebrafish

The ease of use and robustness of genome editing by CRISPR/Cas9 has led to successful use of gene knockout zebrafish for disease modeling. However, it still remains a challenge to precisely edit the zebrafish genome to create single-nucleotide substitutions, which account for ~60% of human disease-c...

詳細記述

書誌詳細
主要な著者: Blake Carrington, Rachel N. Weinstein, Raman Sood
フォーマット: 論文
言語:English
出版事項: MDPI AG 2020-07-01
シリーズ:Cells
主題:
オンライン・アクセス:https://www.mdpi.com/2073-4409/9/7/1690