BE4max and AncBE4max Are Efficient in Germline Conversion of C:G to T:A Base Pairs in Zebrafish

The ease of use and robustness of genome editing by CRISPR/Cas9 has led to successful use of gene knockout zebrafish for disease modeling. However, it still remains a challenge to precisely edit the zebrafish genome to create single-nucleotide substitutions, which account for ~60% of human disease-c...

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Bibliografische gegevens
Hoofdauteurs: Blake Carrington, Rachel N. Weinstein, Raman Sood
Formaat: Artikel
Taal:English
Gepubliceerd in: MDPI AG 2020-07-01
Reeks:Cells
Onderwerpen:
Online toegang:https://www.mdpi.com/2073-4409/9/7/1690