BE4max and AncBE4max Are Efficient in Germline Conversion of C:G to T:A Base Pairs in Zebrafish

The ease of use and robustness of genome editing by CRISPR/Cas9 has led to successful use of gene knockout zebrafish for disease modeling. However, it still remains a challenge to precisely edit the zebrafish genome to create single-nucleotide substitutions, which account for ~60% of human disease-c...

Full beskrivning

Bibliografiska uppgifter
Huvudupphovsmän: Blake Carrington, Rachel N. Weinstein, Raman Sood
Materialtyp: Artikel
Språk:English
Publicerad: MDPI AG 2020-07-01
Serie:Cells
Ämnen:
Länkar:https://www.mdpi.com/2073-4409/9/7/1690