miR-224-5p and miR-545-5p Levels Relate to Exacerbations and Lung Function in a Pilot Study of X-Linked MicroRNA Expression in Cystic Fibrosis Monocytes

miR-224-5p and miR-545-5p Levels Relate to Exacerbations and Lung Function in a Pilot Study of X-Linked MicroRNA Expression in Cystic Fibrosis Monocytes

Altered microRNA expression patterns in bronchial brushings from people with versus without cystic fibrosis (CF) relate to functional changes and disease pathophysiology. The expression of microRNAs encoded on the X chromosome is also altered in peripheral blood monocytes of p. Phe508del homozygous...

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Bibliographic Details
Main Authors: Paul J. McKiernan, Kevin P. Molloy, Arlene M. A. Glasgow, Noel G. McElvaney, Catherine M. Greene
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Genetics
Subjects:
x-linked miRNAs
cystic fibrosis
x chromosome
miR-224-5p
miR-545-5p
Smad4
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.739311/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.739311/full

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