In the Model Host <i>Caenorhabditis elegans</i>, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria

In the Model Host <i>Caenorhabditis elegans</i>, Sphingosine-1-Phosphate-Mediated Signaling Increases Immunity toward Human Opportunistic Bacteria

Sphingosine-1-phophate (S1P) is a sphingolipid-derived signaling molecule that controls diverse cellular functions including cell growth, homeostasis, and stress responses. In a variety of metazoans, cytosolic S1P is transported into the extracellular space where it activates S1P receptors in a conc...

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Bibliographic Details
Main Authors: Kiho Lee, Iliana Escobar, Yeeun Jang, Wooseong Kim, Frederick M. Ausubel, Eleftherios Mylonakis
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
<b>Keywords</b>: Sphingosine-1-phosphate
S1P
S1P kinase
S1P transporters
pathogenic bacteria
immunity
Online Access:https://www.mdpi.com/1422-0067/21/21/7813

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https://www.mdpi.com/1422-0067/21/21/7813

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