The KIR repertoire of a West African chimpanzee population is characterized by limited gene, allele, and haplotype variation

The KIR repertoire of a West African chimpanzee population is characterized by limited gene, allele, and haplotype variation

IntroductionThe killer cell immunoglobulin-like receptors (KIR) play a pivotal role in modulating the NK cell responses, for instance, through interaction with major histocompatibility complex (MHC) class I molecules. Both gene systems map to different chromosomes but co-evolved during evolution. Th...

Full description

Bibliographic Details
Main Authors: Natasja G. de Groot, Corrine M.C. Heijmans, Marit K.H. van der Wiel, Jesse Bruijnesteijn, Ronald E. Bontrop
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
KIR
MHC-C
haplotype
chimpanzee
human
next generation sequencing (NGS)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1308316/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1308316/full

Similar Items