Driving an Oxidative Phenotype Protects Myh4 Null Mice From Myofiber Loss During Postnatal Growth

Driving an Oxidative Phenotype Protects Myh4 Null Mice From Myofiber Loss During Postnatal Growth

Postnatal muscle growth is accompanied by increases in fast fiber type compositions and hypertrophy, raising the possibility that a slow to fast transition may be partially requisite for increases in muscle mass. To test this hypothesis, we ablated the Myh4 gene, and thus myosin heavy chain IIB prot...

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Bibliographic Details
Main Authors: Caiyun Zeng, Hao Shi, Laila T. Kirkpatrick, Aymeric Ricome, Sungkwon Park, Jason M. Scheffler, Kevin M. Hannon, Alan L. Grant, David E. Gerrard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Physiology
Subjects:
myosin heavy chain
clenbuterol
oxidative metabolism
muscle fiber type
PGC-1α
myostatin
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.785151/full

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https://www.frontiersin.org/articles/10.3389/fphys.2021.785151/full

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