Driving an Oxidative Phenotype Protects Myh4 Null Mice From Myofiber Loss During Postnatal Growth
Postnatal muscle growth is accompanied by increases in fast fiber type compositions and hypertrophy, raising the possibility that a slow to fast transition may be partially requisite for increases in muscle mass. To test this hypothesis, we ablated the Myh4 gene, and thus myosin heavy chain IIB prot...
Main Authors: | Caiyun Zeng, Hao Shi, Laila T. Kirkpatrick, Aymeric Ricome, Sungkwon Park, Jason M. Scheffler, Kevin M. Hannon, Alan L. Grant, David E. Gerrard |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-02-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.785151/full |
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