The Relationship between Iron and LRRK2 in a 6-OHDA-Induced Parkinson’s Disease Model

The pathogenesis of Parkinson’s disease (PD) is very complex and still needs further exploration. Leucine-rich repeat kinase 2 (LRRK2) is associated with familial PD in mutant forms and sporadic PD in the wild-type form. Abnormal iron accumulation is found in the substantia nigra of PD patients, but...

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Bibliographic Details
Main Authors: Ruru Jia, Yanling Liu, Ke Shuai, Cheng Zhou, Lei Chen, Li Zhu, Xiao-Mei Wu
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/4/3709