Effect of sevoflurane and propofol on tourniquet-induced endothelial damage: a pilot randomized controlled trial for knee-ligament surgery

Abstract Background The glycocalyx layer is a key structure in the endothelium. Tourniquet-induced ischemic periods are used during orthopedic surgery, and the reactive oxygen species generated after ischemia-reperfusion may mediate the shedding of the glycocalyx. Here, we describe the effects of to...

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Bibliographic Details
Main Authors: Felipe Maldonado, Diego Morales, Rodrigo Gutiérrez, Maximiliano Barahona, Oscar Cerda, Mónica Cáceres
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Anesthesiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12871-020-01030-w