A Proximity biotinylation assay with a host protein bait reveals multiple factors modulating enterovirus replication.

As ultimate parasites, viruses depend on host factors for every step of their life cycle. On the other hand, cells evolved multiple mechanisms of detecting and interfering with viral replication. Yet, our understanding of the complex ensembles of pro- and anti-viral factors is very limited in virtua...

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Bibliographic Details
Main Authors: Seyedehmahsa Moghimi, Ekaterina G Viktorova, Samuel Gabaglio, Anna Zimina, Bogdan Budnik, Bridge G Wynn, Elizabeth Sztul, George A Belov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010906