The MASTL-ENSA-PP2A/B55 axis modulates cisplatin resistance in oral squamous cell carcinoma
Platinum-based chemotherapy is the standard first-line treatment for oral squamous cell carcinoma (OSCC) that is inoperable, recurrent, or metastatic. Platinum sensitivity is a major determinant of patient survival in advanced OSCC. Here, we investigated the involvement of MASTL, a cell cycle kinase...
Auteurs principaux: | , , , , , , |
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Format: | Article |
Langue: | English |
Publié: |
Frontiers Media S.A.
2022-09-01
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Collection: | Frontiers in Cell and Developmental Biology |
Sujets: | |
Accès en ligne: | https://www.frontiersin.org/articles/10.3389/fcell.2022.904719/full |