Dysbiosis of the intestinal fungal microbiota increases lung resident group 2 innate lymphoid cells and is associated with enhanced asthma severity in mice and humans

Abstract Background The gut-lung axis is the concept that alterations of gut microbiota communities can influence immune function in the lungs. While studies have explored the relationship between intestinal bacterial dysbiosis and asthma development, less is understood about the impact of commensal...

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Bibliographic Details
Main Authors: Amjad N. Kanj, Theodore J. Kottom, Kyle J. Schaefbauer, Malay Choudhury, Andrew H. Limper, Joseph H. Skalski
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02422-5