Zebrafish small molecule screens: Taking the phenotypic plunge

Target based chemical screens are a mainstay of modern drug discovery, but the effectiveness of this reductionist approach is being questioned in light of declines in pharmaceutical R & D efficiency. In recent years, phenotypic screens have gained increasing acceptance as a complementary/alterna...

Full description

Bibliographic Details
Main Authors: Charles H. Williams, Charles C. Hong
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037016300447