Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs

Abstract Background Iron oxide nanoparticles have been approved by food and drug administration for clinical application as magnetic resonance imaging (MRI) and are considered to be a biocompatible material. Large iron oxide nanoparticles are usually used as transversal (T 2) contrast agents to exhi...

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Bibliographic Details
Main Authors: Lin Wu, Wen Wen, Xiaofeng Wang, Danhua Huang, Jin Cao, Xueyong Qi, Song Shen
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Particle and Fibre Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s12989-022-00465-y