Intra-articular delivery of micronized dehydrated human amnion/chorion membrane reduces degenerative changes after onset of post-traumatic osteoarthritis

Intra-articular delivery of micronized dehydrated human amnion/chorion membrane reduces degenerative changes after onset of post-traumatic osteoarthritis

Background: Micronized dehydrated human amnion/chorion membrane (mdHACM) has reduced short term post-traumatic osteoarthritis (PTOA) progression in rats when delivered 24 h after medial meniscal transection (MMT) and is being investigated for clinical use as a disease modifying therapy. Much remains...

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Bibliographic Details
Main Authors: Angela S. P. Lin, David S. Reece, Tanushree Thote, Sanjay Sridaran, Hazel Y. Stevens, Nick J. Willett, Robert E. Guldberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
osteoarthritis
amniotic membrane
intra-articular
delayed treatment
medial meniscal transection
3D EPIC-μCT
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1224141/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1224141/full

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