5-Aminolevulinic acid induced fluorescence is a powerful intraoperative marker for precise histopathological grading of gliomas with non-significant contrast-enhancement.

5-Aminolevulinic acid induced fluorescence is a powerful intraoperative marker for precise histopathological grading of gliomas with non-significant contrast-enhancement.

Intraoperative identification of anaplastic foci in diffusely infiltrating gliomas (DIG) with non-significant contrast-enhancement on MRI is indispensible to avoid histopathological undergrading and subsequent treatment failure. Recently, we found that 5-aminolevulinic acid (5-ALA) induced protoporp...

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Bibliographic Details
Main Authors: Georg Widhalm, Barbara Kiesel, Adelheid Woehrer, Tatjana Traub-Weidinger, Matthias Preusser, Christine Marosi, Daniela Prayer, Johannes A Hainfellner, Engelbert Knosp, Stefan Wolfsberger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3800004?pdf=render

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http://europepmc.org/articles/PMC3800004?pdf=render

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